The Wistar rats in the treatment groups received the daily dosage of 250 mg of the test substances (Ca-Alg aerogel or Na-Alg) for 15 days, and they were sacrificed on day 16. Some Wistar strains seem to be derived from Metabolic features in disease-resistant as well as in spontaneously hypertensive rats and newly established obese Wistar Ottawa Karlsburg inbred rats. J. Natl. In addition, they did not respond to acute administration of either desipramine or 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2000. • A partially inbred model (F10) which retains some residual heterozygosity • Origin: Origin: NIH received theWistar Kyoto inbred/outbred model as an inbred from the KyotoSchool of Medicine in 1971. Forty inbred SD rats consisting of 20 each of weanling male and female weighing between 117– 264g and 82-116g respectively (at the commencement of the study) were used. In three experiments we have studied the effects of acute administration of various doses (5, 10, 15 and 25 mg/kg) of desipramine (DMI) and two doses (0.5 and 2 mg/kg) of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), a selective 5HT 1A receptor agonist, on behaviour of five inbred strains of rats in the holeboard and the forced swimming test (FST). van den Brandt, J., Kovács, P. & Klöting, I. Metabolic features in disease-resistant as well as in spontaneously hypertensive rats and newly established obese Wistar Ottawa Karlsburg inbred rats. Wistar rats have evolved themselves with humans; they eat equivalent food as humans. Species. J. KEY WORDS • hypertension • genetics • Wistar-Kyoto rats • spontaneously hypertensive rats • inbred strains I N 1963, Okamoto and Aoki1 reported from Kyoto, Japan, that they had selectively bred Wistar rats to be spontaneously hypertensive. Transplant. The new inbred WKY/lj-tf rats are heavier than either WKY/lj-cr or SHR/lj-cr, have unique allelic variants, exhibit a higher level of arterial pressure than our inbred WKY/lj-cr rats, are intermediate in HR between SHR/lj-cr and WKY/lj-cr rats, exhibit greater circadian variation especially during a high NaCl diet, and show salt sensitivity for arterial pressures. Wistar-Kyoto rats are reported to be very passive in the forced swimming test. Animal Technology 37, 109-112. Previously, we reported that Wistar–Imamichi (WI) rats are highly resistant to cadmium (Cd)-induced lethality and hepatotoxicity compared to Fischer 344 (F344) rats. rats and Wistar King A Hokkaido (WKAH) rats, an inbred strain of Wistar rats. Abdeljalil Lahmanie, Antonio Armario. Abstract. No other significant differences were found. Wistar rat is another common hybrid albino model animal. Wistar Furth rats were significantly quicker to respond than Noble (P < 0.01) and marginally quicker than Brown Norway (P ¼ 0.05) rats. Research output: Contribution to journal › Article › Research › peer-review. Another set of strains were created by mating the outbred col- Kitano M., Hatano H., and Shisa H. (1992) Strain difference of susceptibility to 4-nitroquinoline 1-oxide- induced tongue carcinoma in rats. Although Slc:Wistar rats are used widely in biomedical research as outbred rats, close similarities in growth curves, survival rates, and immunological and biochemical phenotypes have been reported between Slc:Wistar and F344 inbred rats. Wistar rats reproduce quickly; they give birth too many children during a short span of life. osti.gov journal article: distribution and dynamics of rubidium-86 in "inbred" rat stock of the wistar race They can be obtained in large quantities of commercial procedures. an inbred strain of rats, homozygous at most loci, produced by strict brother-sister inbreeding over many generations to develop animals for research with the same general genetic composition. "Rats, Inbred WF" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Abstract. (1986) Length of gestation period in eight inbred strains and three outbred stocks of rats. ing the Wistar colony, and by 1920, there were two colonies (“inbred” and “outbred”) of Wistar rats. Taconic received stock at F10 from the NIHAnimalGenetic Resource in 1974.The rats … Reserpine (RES) is an irreversible inhibitor of VMAT2 used to study Parkinson’s disease (PD) and screening for antiparkinsonian treatments in rodents.… Charles River stocks and strains are managed under the International Genetic Standardization (IGS) program, a unique program designed to manage the health Kim U., Clifton K. H., and Furth J. While the satellite groups were treated for the same duration as that for the treatment groups, but were rather kept under observation for an additional 15 days post treatment, and they were sacrificed on day 30. Although Slc:Wistar rats are used widely in biomedical research as outbred rats, close similarities in growth curves, survival rates, and immunological and biochemical phenotypes have been reported between Slc:Wistar and F344 inbred rats. 11, 184-189. In three experiments we have studied the effects of acute administration of various doses (5, 10, 15 and 25 mg/kg) of desipramine (DMI) and two doses (0.5 and 2 mg/kg) of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), a selective 5HT1A receptor agonist, on behaviour of five inbred strains of rats in the holeboard and the forced swimming test (FST). Wistar rats and Syrian hamsters were fed with or without various concentrations of Chlorella pyrenoidosa contained high-fat diet (CHFD) for 2, 4 and 8 weeks prior to assay of serum lipids. [ Wistar … Peters A. Why are Wistar Rats used in Research History of Wistar Rat Developement. 26 S. NakaNiShi, T. Serikawa, aND T. kuramoTo DuCrj inbred rats [3]. Cancer Inst. Description Price Currency; 3-4 weeks, up to 60g approx weight: 230.20: USD: 4-5 weeks, 61-85g approx weight Jpn. Although Slc:Wistar rats are used widely in biomedical research as outbred rats, close similarities in growth curves, survival rates, and immunological and biochemical phenotypes have been reported between Slc:Wistar and F344 inbred rats. Direct evidence for a stem cell common to hematopoiesis and its in vitro microenvironment: studies on syngeneic (inbred) Wistar Furth rats Subjects. (1960) A highly inbred strain of Wistar rats yielding spontaneous mammo-somatotropic pituitary and other tumors. Inbred Rats - WF/NHsd - 012. 24, 1031-1055. Many subsequent strains were derived from the outbred Wistar commercial stock (e.g., Lewis, Buffalo, Wistar Kyoto).